Bypassing the side effects of thiazolidinediones?
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چکیده
منابع مشابه
Effectiveness and side effects of thiazolidinediones for type 2 diabetes.
OBJECTIVE To assess effectiveness and side effects of thiazolidinediones (TZDs) as adjunctive therapy in suboptimally controlled patients with type 2 diabetes. DESIGN AND SETTING Review of a prospectively recorded database at the Royal Melbourne Hospital diabetes clinic. PARTICIPANTS 203 patients with type 2 diabetes who received pioglitazone or rosiglitazone between 1 May 2000 and 31 Octob...
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A comparison in a clinical setting of the efficacy and side effects of three thiazolidinediones.
T h ree thiazolidinediones (TZDs) are c u rrently available for clinical use in the U.S.: troglitazone, ro s i g l i t a z o n e , and pioglitazone. Because we are aware of no comparative studies of these thre e agents, we wish to re p o rt our initial experience with their efficacy in lowering glucose and improving dyslipidemia, as well as their side eff e c t s. When clinically indicated, pat...
متن کاملAntiatherogenic effects of thiazolidinediones?
Treatment of type 2 diabetes mellitus (DM) is directed at relieving symptoms of hyperglycemia and reducing the incidence of diabetes-associated pathologies. Complications of atherosclerosis, including myocardial infarction and stroke, are the most common causes of death in diabetic patients. Thiazolidinediones (TZDs) represent a relatively recent addition to the arsenal of pharmaceutical option...
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ژورنال
عنوان ژورنال: Nature Reviews Drug Discovery
سال: 2007
ISSN: 1474-1776,1474-1784
DOI: 10.1038/nrd2363